Viagra – The Story Of Wonderpill

decades

Who would have thought 8 decades back that sildenafil citrate, a medication used for the treatment of angina pectoris (a cardiovascular disease), could work wonders for treating male erectile dysfunction (ED)? The results were astonishing. The drug was less effective for angina but supplied astonishing results in treating ED. It was improved in 1996 from the drug company Pfizer and approved for use in ED from the FDA on March 27, 1998. No other medication was approved before in the US to treat ED.

Pfizer used brand name’Viagra’ for its hitherto new product. Another theory is ‘Viagra’ originates from the Sanskrit word”vya-ghra”, meaning tiger. Viagra can be informally known as”Vitamin V”,”that the Blue Pill”,”the Wonder Pill” and several other nicknames. It’s a prescription drug and must be taken after thorough consultation with the doctor cialis.

The reasons for the popularity of Viagra are obvious. The causes of such impotence may be psychological, resulting from stress, fatigue, anxiety, or depression. But over 90 percent of their time, there are recognizable biological issues. The ED or impotence is prominent amongst men over 50 due to various hormonal changes within the body. This could cause partial or total loss of sexual functioning. It is here that Viagra scores across the traditional therapy choices including penile implants, injectable medications (into the penis), and vacuum constriction devices.

Simply, Viagra retains the smooth muscle of penis relaxed. A relaxed manhood allows good blood flow in and generation of an erection.

Viagra works in sync with the natural processes of the body. It blocks the action of type 5 phosphodiesterase enzyme (PDE5). This enzyme, in turn, promotes the accumulation of cyclic guanosine monophosphate (cGMP), a chemical which causes a decline in the amount of calcium within a muscle cell. This, then, contributes to relaxation of that muscle cell and promotes penile erection. The more cGMP inside the cell, the greater the erection will be. However, cGMP is broken down by the PDE5 receptor, which will be offered in large supply in the penis. This is the reason Viagra’s ability to block the action of PDE5 is so essential. The medication allows the accumulation of cGMP, which allows an erection to develop and be maintained.

Negative Effects

The likelihood of side effects increase as the dose gets stronger. Some of the unwanted effects of Viagra are –

Overall, despite the obvious risks, Viagra is an incredible favorable development for men suffering from erectile dysfunction.

Other Advantages

Recent studies have found that Viagra can reduce the effects of strain on the heart. Scotland on Sunday has just reported that consultants at York hill Children’s Hospital in Glasgow are utilizing Viagra as a life-saving cure for kids suffering from pulmonary hypertension, an effect of so-called”blue baby” syndrome that affects the blood flow into the lungs.

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